21c Museum Hotel St. Louis brings a bright, easygoing energy to Downtown, and it is the kind of stay that makes a St. Louis trip feel special from the moment you arrive. With its welcoming spaces and a location that keeps the city close, it is a happy base for exploring the Gateway City.
Set in Downtown, the hotel puts you near some of St. Louis’ favorite sights — from the Gateway Arch and the Mississippi riverfront to Busch Stadium, Forest Park and the city’s museums, music venues and neighborhood restaurants. Getting around is simple, so more of your trip goes to exploring and less to planning.
What guests love most is easy to picture: 1926 ymca building turned museum-hotel with free art galleries, plus idol wolf restaurant by chef ben grupe. Add indoor pool in the historic natatorium space, and you have a stay that balances comfort, character and convenience in equal measure.
Perfect for art travelers and food lovers.
Your St. Louis getaway is one click away: Book this hotel on Expedia
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Photos: 21c Museum Hotel St. Louis and partners
