Some hotels simply get San Francisco — and The St. Regis delivers it with five-star grace. Rising over the SoMa district steps from SFMOMA and the Moscone Center, this landmark stay pairs timeless elegance with the city’s creative pulse, from its celebrated on-site restaurant Astra to a 24-hour indoor pool that keeps the good vibes going around the clock.
Set at 125 Third Street, The St. Regis puts you in the heart of it all: world-class museums, the Yerba Buena Gardens, and downtown’s best shopping and dining are all an easy stroll away. Guest rooms and suites blend classic refinement with thoughtful touches, and the fitness center and spa-style pool make unwinding effortless after a day of exploring.
This is the stay for travelers who want the very best of San Francisco — romantics, culture lovers, and anyone celebrating something special. Every detail feels polished, personal, and unmistakably St. Regis.
Ready for five-star San Francisco? Book this hotel on Expedia
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Photo: Expedia
